Recently i configured Autofac with ASP.Net MVC 4 and WebAPI. Here are the steps required to configure Autofac
  1. Install package Autofac.MVC4
  2. Install package Autofac.WebApi
  3. Add a class AutofacBootstrap. Use this class to configure the dependencies within your project.
  4. Open Global.asax file and add a method like
  5.  Call the method from Application_Start
  6. And you are done !!